Need Tickets to Opening Day? Major League Baseball's 2021 season schedule is set, including MLB Opening Day games. The date for Opening Day of the 2021 MLB season is April 1st. The full schedule of games is available here, and there are Opening Day tickets available for every game. One of the biggest Opening Day games in 2021 will be the Texas Rangers, who are (finally) debuting their new ballpark, Globe Life Field for their fans who did not get to attend Opening Day 2020. Get your seat to all the action with 2021 MLB Tickets from TicketCity.