Need Tickets to Baseball's 2022 Opening Day? Major League Baseball's 2022 season schedule will be released soon so keep checking back here for the latest info. The date for Opening Day of the 2022 MLB season will likely be early April. The full schedule of games will be available here, and there are Opening Day tickets available for every game. Back Opening Day Games in 2022 will include whichever team wins the 2021 World Series and will be receiving their rings and revealing the WS banner. Get your seat to all the action with 2022 MLB Tickets from TicketCity.